One French photo journalist and an American journalist were killed Wednesday morning when the bomb hit a media center in the Syrian city of Homs, local broadcaster France Info reported.
The deaths are the French photographer Ochlik Remi who was working for the magazine Paris-Match and American journalist Marie Colvin who was a special correspondent for the Sunday Times.
The news was also confirmed by French President Nicolas Sarkozy's spokeswoman Nathalie Kosciusko-Morizet.
"The president gave us the sad news, which is apparently confirmed, of the two journalists and notably a French journalist, and asked the government spokeswoman to present our condolences to the families," she said.
Remi is the second French journalist died in Syria. In January French television reporter Gilles Jacquier was killed in Syria, the first Western journalist to die since anti-regime protests erupted 11 months ago.